Organic chemistry is one of the most “feared” classes amongst all undergraduates across the nation; this is partly because organic chemistry forces students to think visually about molecules and see how they can come together to create unique compounds. React! is an innovative and collaborative board game intended to address many of the challenges to learning organic chemistry. Created by a team of students who have proficiently mastered and taught all the subtle aspects of organic chemistry, React! is designed to meet the needs of students learning organic chemistry for the first time. The team has worked hard to structure the game such that players perceive organic chemistry as a challenging, yet rewarding puzzle as opposed to a series of facts to memorize. Ultimately, we hope React! empowers students to think critically about organic chemistry in a collaborative and entertaining environment.